
CELLULAR REJUVENATION
POLYNUCLEOTIDES
Polynucleotides are the fundamental building blocks of DNA, which possess healing and regenerative qualities.
Utilising purified polymerised polynucleotides derived from salmon DNA, this initiates a cascade of effects which stimulate the action of fibroblasts - cells essential for the formation of collagen and elastin.
What it treats
Through their unique mechanisms of action, polynucleotides encourage the production of collagen and elastin, restoring skin elasticity, firmness, and youthfulness.
Treatment areas include any skin area, as well as the hair.
How it works
PDRN is designed to target rejuvenation at the cellular level:
- targeting free radicals and oxidative stress
- triggering and improving tissue regeneration
- restoring skin tone and elasticity
- increasing local vascularisation for the free flow of nutrients.










Polynucleotides
What to expect
Prior to the procedure, we will have a full consultation to get a good understanding of your treatment goals.
Depending on the technique used, numbing cream may be applied, then the solution is administered under the skin.
Suitablity
Ameela is suitable for all, with a range of indications including the signs of ageing, however can be seen as an alternative to tear-trough filler for those that would like to rejuvenate the eye area.
This treatment is not suitable if you are pregnant, breastfeeding, vegan or vegetarian, as the polynucleotides are derived from salmon, however is suitable in the case of fish allergies.
Downtime
There is minimal downtime with this treatment. There will be bumps at the injection site, which can take a day or two to settle. Bruising at the injection site is also possible.
Recommended Course
This will be determined during consultation. 2-3 treatments may be required, with 2-week intervals.
How long does it last?
To maintain the rejuvenating effects, we recommend 1 treatment every 6-9 months.
Are there any risks involved?
The polynucleotides used in Ameela are purified, making them free from other components, such as proteins, which can trigger an immune response.
Polynucleotides have a high safety profile with a low risk of vascular occlusion. They have a direct action, and do not proliferate abnormal cellular activity.
What brand do you use?
To ensure safe and effective results, at Privi Studios we use Ameela or Plinest polynucleotides.
Is it a filler?
Traditional dermal fillers are made of a cross-linked hyaluronic acid gel. This gel retains its structure when injected and is used to add volume to the treatment area.
Polynucleotides are small fragments of purified salmon DNA, suspended in a water base. It is not cross-linked and does not form or leave any solid state within the skin tissue. There will be an initial volume once injected that settles within 1-2 days, and any volume thereafter is due to the stimulation of fibroblasts and collagen production.
Pre & Post Care
Preparing for your appointment
Please ensure your appointment is scheduled two weeks after any heat/energy based treatments, epilation and waxing to avoid hypersensitivity.
After your treatment
Avoid foundation or creams over the treatment area for 6 hours after your treatment.
Avoid strenuous exercise first 24 hours or hot tubs.
Avoid alcohol for 24 hours after your treatment.
No saunas or tanning booths for 2 weeks after your treatment
No Radiofrequency, IPL, laser, or any other heat treatments near the treated area for 2 weeks.
Always wear a broad spectrum, high factor (30 or above) SPF.
Bruising can be helped by taking oral bromelain (pineapple extract) and oral arnica, or by applying arnica cream.
After your treatment, you should begin to see an improvement skin quality, skin hydration and texture when the swelling subsides, but you’ll need to give it 3-7 days to settle. Thereafter, the bio-revitalisation and collagen stimulation continues for 90 days,
It’s important to have your second follow up treatment to achieve the best results.
